Guidelines Pap Smear

NIAID guidelines pap smear ASCUS results with recommendations of repeat pap smears, and HPV DNA testing and cervical colposcopy and biopsy of suspicious areas, e.g. genital wart. Clinical analysis will vary among the interpreters of a borderline atypical cytology result (ASCUS). This condition can disappear untreated, and sometimes it can progress. Since HPV infection is linked in almost all cases of cervical cancer, HPV DNA testing on the original specimen can provide greater quality assurance. NIAID guidelines pap smear ASCUS results with recommendations of repeat pap smears, and HPV DNA testing and cervical colposcopy and biopsy of suspicious areas, e.g. genital wart.

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Recommended procedures for the management of atypical cytology cases list a 4-6 month repeat, a cervical colposcopy and biopsy of the suspicious areas, and HPV DNA testing meet their criteria as prudent and feasible. More severe cases of abnormal require further diagnostic measures. Typically these are surgically invasive procedures. NIAID guidelines pap smear ASCUS results with recommendations of repeat pap smears, and HPV DNA testing and cervical colposcopy and biopsy of suspicious areas, e.g. genital wart.

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